Allergy Profile 70

Home / Lab Tests / Allergy Profile 70

A B
1
Test Code: 815 ALLERGY PROFILE 70
2
Performing Lab:  SMA Specialty Medical Lab
3
Clinical Significance:  Detect possible allergic responses to various foods and substances in the environment (see Test Includes) and evaluate for hay fever, asthma, atopic eczema, and respiratory allergy. The quantitative allergen-specific IgE test is indicated
• to determine whether an individual has elevated allergen-specific IgE antibodies;
• if specific allergic sensitivity is needed to allow immunotherapy to be initiated;
• when testing individuals for agents that may potentially cause anaphylaxis;
• when evaluating individuals who are taking medication (eg, long-acting antihistamines) that may interfere with other testing modalities (eg, skin testing);
• if immunotherapy or other therapeutic measures based on skin testing results have not led to a satisfactory remission of symptoms;
• when an individual is unresponsive to medical management where identification of offending allergens may be beneficial
4
Results Interpretation:  Calss 0: <0.10 – 0.34 KU/L
5
Calss I: 0.35 – 0.69 KU/L
6
Calss II: 0.70 – 3.49 KU/L
7
Calss III: 3.50 – 17.4 KU/L
8
Calss IV: 17.5 – 52.4 KU/L
9
Calss V: 52.5 – 99.9 KU/L
10
Class VI: >100 KU/L
11
Preferred Specimen:  Serum collected in Serum Separator Tube or Red Top Tube
12
Alternate Specimen If a red-top tube is used, transfer separated serum to a plastic transport tube
13
Volume:  5 mL
14
Specimen Container:  Gel Barrier Tube (Serum Separator Tube); Red Top Tube; Plastic Transfer Tube
15
Collection Separate serum from cells within 45 minutes of collection
16
Transport Temperature:  Refrigerated
17
Specimen Stability:  Refrigerated: 7 days
18
Causes for Rejection  Improper labeling; plasma; hemolyzed sample; grossly lipemic sample
19
Methodology:  Chemiluminescent Immunoassay
20
Setup Days:  Daily, no weekends
21
Setup Times:  7 AM – 1 PM
22
Turnaround:  3 days
23
CPT Code(s):  86003
24
(The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.)
25
Instrument IMMULITE 2000
26
Test Components IgE, Total
27
D1 Dermatophagoides Pteronyssinus
28
D2 Dermatophagoides Farinae
29
E1 Cat Dander-Epithelium
30
E2 Dog Dander
31
E3 Horse Dander
32
E5 Dog Dander
33
E80 Goat Epithelium
34
E81 Sheep Epithelium
35
E85 Chicken Feathers
36
E86 Duck Feathers
37
E89 Turkey Feathers
38
E91 Parrot Feather
39
E201 Canary Feather
40
G2 Bermuda Grass
41
G3 Orchard Grass
42
G4 Meadow Fescue
43
G5 Perennial Rye Grass
44
G8 Kentucky Blue Grass (June Grass)
45
G9 Red Top Grass
46
G10 Johnson Grass
47
G11 Brom Grass
48
G14 Cultivated Oat Grass
49
G17 Bahia Grass
50
I206 American Cockroach
51
I6 Cockroach
52
M3 Aspergillus Fumigatus
53
M5 Candida Albicanis
54
M6 Alternaria Tenuis
55
M10 Stemphylium Botryos
56
M11 Rhizopus Nigricans
57
M14 Epicoccum Purpur
58
T1 Maple
59
T2 Red Alder
60
T3 Birch
61
T5 American Beech
62
T8 Elm
63
T9 Olive Tree
64
T10 Walnut Pollen
65
T11 American Sycamore
66
T12 Black Willow
67
T14 Cottonwood
68
T15 White Ash
69
T16 White Pine
70
T18 Eucalyptus/Blue Gum
71
T19 Acacia
72
T20 Mesquite
73
T43 Loblolly Pine
74
T70 White Mulberry
75
T72 Queen Palm
76
T77 Oak Mix
77
T210 Privet
78
T211 Sweet Gum
79
W1 Common Ragweed
80
W3 Giant Ragweed
81
W6 Mugwort
82
W9 English Plantain
83
W10 Lamb's Quarters
84
W11 Russian Thistle
85
W12 Goldenrod
86
W13 Cocklebur
87
W14 Rough Pigweed
88
W15 Scale
89
W16 Rough Marsh Elder
90
W17 Firebush (Kochia)
91
W18 Sheep Sorrel
92
W20 Nettle
93
W46 Dog Fennel
94
W82 Carless Weed

ComprehensiveDx Clear™


ComprehensiveDx Clear™
Test Code: 1248
Test Description ComprehensiveDx Clear is a comprehensive panel for hereditary breast, ovarian, uterine, colorectal, pancreatic, prostate and melanoma cancers.
Genes Tested GENE ASSOCIATED CANCER(S) SYNDROME
APC Colorectal, pancreatic and other Familial Adenomatous Polyposis syndrome, Gardner syndrome, and Turcot syndrome
ATM Breast, pancreatic Ataxia-telangiectasia (if both copies of the gene are mutated)
BAP1 Renal, melanoma, mesothelioma Familial Melanoma Cancer Syndrome
BARD1 Breast, ovarian
BMPR1A Colorectal, gastric, pancreatic Juvenile Polyposis syndrome
BRCA1 Breast, ovarian, pancreatic, prostate, male breast Hereditary Breast and Ovarian Cancer syndrome
BRCA2 Breast, ovarian, pancreatic, prostate, male breast, melanoma Hereditary Breast and Ovarian Cancer syndrome;
Fanconi anemia (if both copies of the gene are mutated)
BRIP1 Ovarian, breast Fanconi anemia (if both copies of the gene are mutated)
CDH1 Breast, gastric, colorectal Hereditary Diffuse Gastric Cancer
CDK4 Melanoma, pancreatic Familial Melanoma Cancer Syndrome
CDKN2A Melanoma, pancreatic Familial Melanoma Cancer Syndrome
CHEK2 Breast, colorectal
DICER1 Lung, kidney, thyroid, ovarian
EPCAM Colorectal, gastric, endometrial, ovarian Lynch (Hereditary non-polyposis colon cancer) syndrome
FANCC Breast Fanconi anemia (if both copies of the gene are mutated)
MRE11A Breast, ovarian Ataxia-telangiectasia-like Syndrome (if both copies of the gene are mutated)
MSH2 Colorectal, gastric, endometrial, ovarian Lynch (Hereditary non-polyposis colon cancer) syndrome
MSH6 Colorectal, endometrial Lynch (Hereditary non-polyposis colon cancer) syndrome
MUTYH Colorectal MUTYH-associated Polyposis syndrome
NBN Breast, melanoma, prostate Nijmegen breakage syndrome (if both copies of the gene are mutated)
PALB2 Breast, ovarian, pancreatic, male breast Fanconi anemia (if both copies of the gene are mutated)
PMS2 Colorectal, endometrial, gastric, ovarian Lynch (Hereditary non-polyposis colon cancer) syndrome
POLD1 Colorectal, endometrial Familial Adenomatous Polyposis syndrome
POLE Colorectal, gastrointestinal Familial Adenomatous Polyposis syndrome
PTEN Breast, uterine, colorectal, thyroid, kidney, melanoma Cowden Syndrome / PTEN Hamartoma Tumor Syndrome
RAD50 Ovarian
RAD51C Breast, ovarian Fanconi anemia (if both copies of the gene are mutated)
RAD51D Breast, ovarian
SDHA Gastrointestinal, other Paragangliomas 5
SDHB Gastrointestinal, renal, other Paraganglioma and gastric stromal sarcoma
SDHC Gastrointestinal, renal, other Paraganglioma and gastric stromal sarcoma
SDHD Gastrointestinal, renal, other Cowden Syndrome 3; Paraganglioma and gastric stromal sarcoma
SMAD4 Colorectal, gastric Juvenile Polyposis syndrome
STK11 Colorectal, endometrial, gastric, ovarian, breast, pancreatic Peutz-Jeghers syndrome
TP53 Colorectal, breast, pancreatic, sarcomas, gastrointestinal, adrenocortical, leukemia Li-Fraumeni syndrome
Specimen Requirements Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request)
Turnaround Time (TAT) 2-3 weeks

This will close in 0 seconds

BreastDx Clear™


BreastDx Clear™
Test Code: 1250
Test Description BreastDx Clear is a multi-gene test that analyzes 16 breast cancer susceptibility genes. Although all women have some risk of developing breast and/or ovarian cancer at some point in their lives, having a mutation in one of the breast cancer susceptibility genes increases this risk. Men who have a mutation in one of the breast cancer susceptibility genes have an increased risk of breast, prostate, pancreatic, gastric and other cancer types.
Genes Tested GENE ASSOCIATED CANCER(S) SYNDROME
ATM Breast, pancreatic Ataxia-telangiectasia (if both copies of the gene are mutated)
BARD1 Breast, ovarian
BRCA1 Breast, ovarian, pancreatic, prostate, male breast Hereditary Breast and Ovarian Cancer syndrome
BRCA2 Breast, ovarian, pancreatic, prostate, male breast, melanoma Hereditary Breast and Ovarian Cancer syndrome;
Fanconi anemia (if both copies of the gene are mutated)
BRIP1 Ovarian, breast Fanconi anemia (if both copies of the gene are mutated)
CDH1 Breast, gastric, colorectal Hereditary Diffuse Gastric Cancer
CHEK2 Breast, colorectal
FANCC Breast Fanconi anemia (if both copies of the gene are mutated)
MRE11A Ovarian, breast Ataxia-telangiectasia-like Syndrome (if both copies of the gene are mutated)
NBN Breast, melanoma, prostate Nijmegen breakage syndrome (if both copies of the gene are mutated)
PALB2 Breast, ovarian, pancreatic, male breast Fanconi anemia (if both copies of the gene are mutated)
PTEN Breast, uterine, colorectal, thyroid, kidney Cowden Syndrome / PTEN Hamartoma Tumor Syndrome
RAD51C Breast, ovarian Fanconi anemia (if both copies of the gene are mutated)
RAD51D Breast, ovarian
STK11 Breast, ovarian, colorectal, gastric, pancreatic Peutz-Jeghers Syndrome
TP53 Breast, brain, sarcomas, gastrointestinal, adrenocortical, leukemia Li-Fraumeni Syndrome
Specimen Requirements Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request)
Turnaround Time (TAT) 2-3 weeks

This will close in 0 seconds

ColoDx Clear™


ColoDx Clear™
Test Code: 1251
Test Description Colorectal cancer is the fourth most common type of cancer diagnosed in the United States and the second leading cause of cancer-related deaths in the country.
ColoDx Clear is a multi-gene test focused on hereditary colon cancer syndromes. Pathogenic variants (mutations) in high-risk colorectal cancer genes are associated with several hereditary cancer syndromes and increase the risk of cancer in many organs.
Genes Tested GENE ASSOCIATED CANCER(S) SYNDROME
APC Colorectal, pancreatic and other Familial Adenomatous Polyposis syndrome, Gardner syndrome, and Turcot syndrome
BMPR1A Colorectal, gastric Juvenile Polyposis syndrome
EPCAM Colorectal, gastric, endometrial, ovarian Lynch (Hereditary non-polyposis colon cancer) syndrome
MLH1 Colorectal, gastric, endometrial, ovarian Lynch (Hereditary non-polyposis colon cancer) syndrome
MSH2 Colorectal, gastric, endometrial, ovarian Lynch (Hereditary non-polyposis colon cancer) syndrome
MSH6 Colorectal, endometrial Lynch (Hereditary non-polyposis colon cancer) syndrome
MUTYH Colorectal MUTYH-associated Polyposis syndrome
PMS2 Colorectal, endometrial, gastric, ovarian Lynch (Hereditary non-polyposis colon cancer) syndrome
POLD1 Colorectal, endometrial Familial Adenomatous Polyposis syndrome
POLE Colorectal, gastrointestinal Familial Adenomatous Polyposis syndrome
PTEN Colorectal, endometrial, breast, melanoma Cowden syndrome
SMAD4 Colorectal, gastric Juvenile Polyposis syndrome
STK11 Colorectal, endometrial, gastric, ovarian, breast, pancreatic Peutz-Jeghers syndrome
TP53 Colorectal, breast, pancreatic and other Li-Fraumeni syndrome
Specimen Requirements Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request)
Turnaround Time (TAT) 2-3 weeks

This will close in 0 seconds

ProstateDx Clear™


ProstateDx Clear™
Test Code: 1257
Test Description: The ProstateDx Clear™  Panel examines genes associated with an increased risk for prostate cancer.  This test includes both well-established prostate cancer susceptibility genes, as well as candidate genes with limited evidence of an association with prostate cancer.
Genes Tested: ATM, BRCA1, BRCA2, CHEK2, EPCAM, HOXB13, MLH1, MSH2, MSH6,
NBN, PALB2, PMS2, TP53
Specimen Requirements Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer)
or Buccal Swab or Saliva (kits available upon request)
Turnaround Time (TAT) 2-3 weeks

This will close in 0 seconds