A | B | |
---|---|---|
1
|
Test Code: 1307 | APOLIPOPROTEIN B |
2
|
Performing Lab: | SMA Specialty Medical Lab |
3
|
Clinical Significance: | Apolipoprotein B (APO B) is a distinct, lipid-binding protein that is the major protein of all lipoproteins other than high-density lipoprotein (HDL). APO B is essential to the formation and release of lipoproteins into the plasma and interacts with the LDL receptors of peripheral cells thereby functioning in the recognition of cellular receptors for the catabolism of LDL. Studies show a correlation between the development of coronary atherosclerosis and abnormal concentrations of lipoproteins. In atherosclerosis, the inner layer of the arterial wall thickens due to the accumulation of cellular material and deposits of several substances, particularly lipids. Because apolipoproteins are unique markers for the identification and differentiation of lipoproteins, they are the most probable determinants of the structural integrity and functional specificity of lipoproteins.3 Measurement of APO B in serum of patients with significant arteriosclerotic alterations shows APO B levels significantly higher than a normal patient population.4 Abnormal APO B values also occur with dyslipoproteinemias. Adult-onset diabetes and liver diseases including acute hepatitis and fatty liver result in elevated APO B values. Numerous studies suggest that serum apolipoprotein A-1 and apolipoprotein B levels indicate the severity and extent of coronary artery stenosis better than serum total cholesterol and triglyceride. In addition, studies indicate that patients with arteriosclerosis are better distinguished from patients without the disease by the finding of increased plasma apolipoprotein B levels than by the findings of decreased HDL-C and increased LDL-C levels. Measuring both apolipoprotein A-1 and apolipoprotein B and expressing the data as a ratio has been shown to be more effective than apolipoprotein A-1 or apolipoprotein B alone (CAD). High levels indicate increased risk for CAD. |
4
|
Reference Ranges: | Males: 66 -133 mg/dL |
5
|
Feamles: 60 – 117 mg/dL | |
6
|
Preferred Specimen | Serum collected in Serum Separator Tube or Red Top Tube |
7
|
Alternate Specimens | If a red-top tube is used, transfer separated serum to a plastic transport tube |
8
|
Minimum Volume | 1 mL |
9
|
Specimen Container | Gel Barrier Tube (Serum Separator Tube); Red Top Tube; Plastic Transfer Tube |
10
|
Collection | Separate serum from cells within 45 minutes of collection |
11
|
Transport Temperature | Refrigerated |
12
|
Specimen Stability | Refrigerated: 7 days |
13
|
Causes for Rejection | Improper labeling; plasma; hemolyzed sample; grossly lipemic sample |
14
|
Methodology: | Immunoturbidimetric |
15
|
Setup Days: | Monday-Saturday |
16
|
Setup Times: | Every Shift |
17
|
Turnaround: | 24 hours |
18
|
CPT Code(s): | 82172 |
19
|
(The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.) | |
20
|
Instrument | SIEMENS Atellica CH |
-
Lab Tests
- 6-AM (Heroin Metabolite)
- AFP
- Albumin
- Alcohol Biomarkers
- Alcohol Biomarkers, EIA
- Alkaline Phosphatase (ALP)
- Allergy Food Panel
- Allergy Profile 30
- Allergy Profile 40
- Allergy Profile 4409
- Allergy Profile 60
- Allergy Profile 70
- Allergy Profile 75
- Allergy Respiratory Panel
- ALT
- Amphetamines
- Amylase
- ANA Profile
- ANA Screen, (EIA)
- ANA with reflex Cascade
- Anti-Mullerian Hormone (AMH)
- ANTI-TPO
- Apo A
- Apo B
- ASO
- AST (SGOT)
- Barbiturates
- Basic Metabolic Panel
- Benzodiazepines
- Bilirubin direct
- Bilirubin Total
- BNP
- Body Fluid Culture
- BUN (Urea Nitrogen)
- BUPRENORPHINE
- C-Peptide
- CA 15.3
- CA 19.9
- CA125
- CA 27.29
- Calcitonin
- Calcium
- Cannabinoids
- Carbon Dioxide (CO2)
- CBC (with Dif & Retic Count)
- CBC (without diferential)
- CBC(with diff&platelet count)
- CEA
- Childhood Allergy Screen
- Chloride
- Cholesterol
- CK
- CK-MB
- CMDC Drug Screen 10 with conf.
- Cocaine
- Coenzyme Q10
- Compliment C 3
- Compliment C 4
- Comprehensive Metabolic Panel
- Cortisol AM
- Cortisol PM
- Cotinine
- Covid 19, PCR
- Creatinine
- Creatinine, 24-hour urine
- Creatinine, Random Urine
- CRP
- CT NG, NAA
- Cystatin C
- Cytomegalovirus (CMV) IgG Abs
- Cytomegalovirus (CMV) IgM Abs
- D,L-Methamphetamine
- DHEA-S
- Digoxin
- Drug Screen 11 (1116B)
- Drug Screen 11 (1120)
- Drug Screen 11 (1189)
- Drug Screen 11 (1365)
- Drug Screen 11 (1372)
- Drug Screen 11 with conf.
- Drug Screen 13 (1116)
- Drug Screen 13 with conf.
- Drug Screen 14 with conf.
- Drug screen 16
- Drug Screen 17 with conf.
- Drug Screen 18 with conf
- Drug Screen 19
- Drug Screen 19 with conf.
- Drug Screen 3
- Drug Screen 5
- Drug Screen 6
- Drug Screen 7 (1116a)
- Drug Screen 7 (512A)
- Drug Screen 7 (512C)
- Drug Screen 8
- Drug Screen 9 (1120A)
- Drug Screen 9 (1120B)
- Drug Screen 9 (1120d)
- Drug Screen 9 (512)
- Drug Screen 9 with confirmation
- Drug Screen-13 with conf
- Drug Screen-18 with conf.
- Drugs Screen 13 (1366)
- EBV Panel
- Ecstasy (MDMA)
- EDDP (METHADONE METABOLITE)
- Electrolyte Panel
- ESR
- Estradiol
- EtG
- Ethanol
- Fasting Blood Sugar
- Ferritin
- Folate II
- Food Panel 30
- Fructosamine
- FSH
- Genital Tract Culture
- GGT
- Glucose Serum
- GlycoMark
- GTT, 100g
- GTT, 50g
- GTT, 75g
- GTT, Postprandial
- H.PILORY
- HCG, TOTAL
- HCG, Urine
- HDL
- Hemoglobin A1C
- Hemoglobin-Hematocrit
- Hepatic Function Panel
- Hepatitis A Ab Total
- Hepatitis A IgM Ab
- Hepatitis B Core Ab Total
- Hepatitis B Core IgM
- Hepatitis Bs Ab, Qualitative
- Hepatitis Bs Ab, Quantitative
- Hepatitis Bs Ag
- Hepatitis Bs Ag conf.
- Hepatitis C Ab
- Hepatitis Panel
- HgB A1c w-reflex to GlycoMark
- HISTOLOGY WORKUP
- HIV
- Homocysteine
- hsCRP
- HSV 1and2 IgG
- Immunoglobulin A
- Immunoglobulin E
- Immunoglobulin G
- Immunoglobulin M
- Immunoglobulin Profile A,G,M
- Insulin
- Iron Saturation (%)
- IRON, TOTAL
- LDH
- LDL, Direct
- LH
- Lipase
- Lipid Panel
- Lithium
- Lp-PLA2 Activity Assay
- Lp(a)
- Lyme Screen wreflex to WB
- Magnesium
- Measles IgG.
- MEPERIDINE
- METHADONE
- Methylmalonic Acid
- Microalbumin
- Microalbumin-Creatinine Ratio
- Microalbumin, 24-hour urine
- MMR+V IgG
- MRSA-culture
- Mumps IgG
- Myoglobin
- NT-proBNP
- Occult Blood
- Opiates
- Oxycodone
- PGX
- Phencyclidine
- Phosphorus
- Platelet Count
- Platelet Count, Citrated Blood
- Potassium
- Potassium, Plasma
- Prealbumin
- Progesterone II
- Prolactin
- Propoxyphene
- Protein Tota, 24-hour urine
- Protein Total
- PSA (total)
- PSA free
- PT INR
- PTH, 1-84
- PTT(activated)
- Renal Function Panel
- Respiratory Panel 30
- Respiratory Profile, PCR
- Reticulocyte Count
- Reverse T3
- Rheumatoid Factor
- RPR
- Rubella IgG
- SARS-CoV-2 IgG Antibodies
- SARS-CoV-2 IgM Antibodies
- SHBG
- Sodium
- Specimen Validity Test
- Sputum Culture
- T3 Total
- T3 Uptake
- T3, FREE
- T4 Free
- T4 Total
- TBG
- TCA
- Testosterone, Free
- Testosterone, Total
- THC-COOH
- THINPREP
- Throat Culture
- Thyroglobulin IgG Ab
- Thyroid Panel
- Thyroid Stimulating Immunoglobulins (TSI)
- TIBC
- Toxicology Oral Fluid
- Toxicology Urine
- Trace Elements (Rendom Urine)
- Trace Elements (Whole Blood)
- Tramadol
- Transferrin
- Treponema Pallidum Ab
- Tryglicerides
- TSH
- TV, NAA
- Uric Acid
- Uric Acid, 24-Hour Urine
- Uric Acid, random urine
- Urinalysis Complete
- Urine Culture Comprehensive
- Urine Culture Routine
- Valproic Acid
- Varicella IgG
- Vitamin A
- Vitamin B1
- Vitamin B12
- Vitamin B2
- Vitamin B3
- Vitamin B5
- Vitamin B6
- Vitamin C
- Vitamin D
- Vitamin D 1,25 OH
- Vitamin E
- Wound Culture